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Set in London, England, good Samaritan Dan Wolf (Jude Law), a struggling writer, takes Alice Ayres (Natalie Portman), a shady young woman and parttime stripper, to the infirmary when she’s hit by a car, and they fall in love. One year later, Dan meets lensman Anna Cameron (Julie Roberts) and tries to pick her up, but she rebuffs him. In revenge, Dan sets Anna up for an sticky meet with sex-addicted skin doctor Larry Bagley (Clive Owen), but the two end up seeing each other. Then some other year later, Dan and Anna begin an affair of their own, and relationships ‘tween the four collapse. Over the next year, all of them become taken up with pain each other and wreak some heavy worked up damage. Will any of them be strong enough to put this destructive succession of events to a stop?
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